cees dekker Things To Know Before You Buy
cees dekker Things To Know Before You Buy
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It had been only in the nineties nevertheless, when nanotechnology had Highly developed to some stage exactly where solitary molecules could be manipulated, that the primary experimental devices began to look.
Multicolor imaging on the bacterial nucleoid and cell division proteins with blue, orange, and near-infrared fluorescent proteins
Since 2000, Dekker has shifted the key aim of his function in direction of biophysics where he scientific studies the Houses of one biomolecules and cells utilizing the tools of nanotechnology. This variation of industry was pushed by his fascination for the exceptional operating of Organic molecular buildings, as well as from the extended-expression point of view that numerous interesting discoveries may be predicted During this industry.[five] Current lines of study in his biophysics group are inside the regions of:[6]
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Immediate immobilization of native yeast iso-one cytochrome c on bare gold: quick electron relay to redox enzymes and zeptomole protein-movie voltammetry
Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with study from DNA supercoiling studies of nucleosomes and DNA maintenance proteins to DNA translocation by nanopores. Just lately his analysis has centered on finding out cell division with bacteria on chip, though his supreme interest is during the route of recognizing artificial cells.
2000, discovery that nanotubes can carry extraordinary huge latest densities; resolved the controversial concern of Digital transportation via DNA molecules by measurements of insulating habits at The one molecule amount; and demonstration of an AFM strategy for one-molecule manipulation of nanotubes
Knowing basic processes regulating the spatial and dynamic organisation in the DNA in Reside cells.
‘The fantastically subtle way by which elements in mother nature operate in no way ceases to amaze me. If we resolve the puzzle of how life arrived into getting, I anticipate that my amazement at the complexity of development can have elevated and with it my awe to the greatness of the Creator.’
Given that 2000 he moved to one-molecule biophysics and nanobiology, with investigation from research of DNA loop extrusion and supercoiling to DNA translocation as a result of nanopores. Far more recently his exploration has focused on finding out chromatin structure and cell division with microbes on chip, even though he is also aiming to ultimately Create artificial cells from the bottom up.
Cees Dekker is Distinguished College Professor at TU Delft. Experienced for a physicist, he pioneered nanotechnology with quite a few discoveries on carbon nanotubes from the nineties. Considering that 2000, he moved to solitary-molecule biophysics and nanobiology. His existing analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, especially SMC motor protein; and (iii) developing a dwelling artificial cell from lifeless molecules. Dekker is an elected member of the KNAW and fellow into the APS as well as IOP.
2008, to start with observation of protein-coated DNA translocation as a result of nanopores; fixed the origin with the electrophoretic pressure on DNA in nanopores; uncovered a major velocity boost of microtubules in electric fields; discovered an anomalous electro-hydrodynamic ceesdekker orientation of microtubules; and fixed the origin of sounds in carbon nanotubes in liquid
Instance (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is demonstrated in grey, the rim on the pore is highlighted in pink, plus a 3D rendering of the motion of your DNA rod is displayed.